Module 1: Coronavirus Emergence & Trajectory: Where and how did COVID-19 start, and where has it spread
Welcome to Session 1: Coronavirus Emergence & Trajectory
This session will explore the origins of COVID-19. We will discuss the epidemiology and pathogenesis of COVID-19 and explain why it is called a novel coronavirus and why this is concerning. We will then delve into the trajectory of COVID-19 both on an international and local level, while examining the large outbreak in Seattle.
Learning Objectives
After completing this module, you will be able to:
- Discuss the epidemiology and pathogenesis of COVID-19
- Explain why COVID-19 became a pandemic and how it spread around the world and in Seattle
Guest Lecturers
Judy Wasserheit, MD, MPH
Links to an external site.
Chair, Global Health
Professor, Global Health
Professor, Medicine - Allergy and Infectious Disease
Adjunct Professor, Epidemiology
Dr. Wasserheit has worked extensively at the interface of sexually transmitted infections (STI) and HIV clinical-epidemiological research, programs and policy in the U.S. and globally. Currently Professor and Chair, of Global Health at the University of Washington, as well as Professor of Medicine and Epidemiology, she was the Founding Chief of the U.S. NIH’s STD Research Branch; Director of the U.S. CDC’s STD/HIV Prevention Program, and Director of the HIV Vaccine Trials Network. She has worked in Bangladesh, Colombia, Egypt, Indonesia, Kenya, Thailand and Zambia. Her development of the concept of epidemiological synergy between HIV infection and other sexually transmitted infections has had a major influence on HIV prevention policy and programs worldwide.
Peter Rabinowitz, MD, MPH
Links to an external site.
Links to an external site.Professor, Global Health
Professor, Env. and Occ. Health Sciences
Professor, Family Medicine
Adjunct Professor, Epidemiology
Adjunct Professor, Medicine - Allergy and Infectious Disease
Dr. Rabinowitz is Professor in the Departments of Environmental and Occupational Health Sciences, Family Medicine, Global Health, Epidemiology, and Medicine (Infectious Disease), University of Washington. He received his BA from Amherst College, his MD from the University of Washington, and completed a Family Medicine residency through UCSF, and fellowships in General Preventive Medicine and Occupational and Environmental Medicine at Yale. He directs the UW Center for One Health Research that serves as an incubator and organizer of research, training, and clinical activities related to the human-animal-ecosystem interface. Focus areas of Center research include microbiome sharing between humans, animals, and environments, antimicrobial resistance, and diagnosis, treatment, and prevention of zoonotic diseases.
Recorded Session (1 hour)
If you missed the live session, watch the recording here.
Slides: Download Slides: Judy Wasserheit
Slides: Download Slides: Peter Rabinowitz
Download MP4 113MB Links to an external site.
Readings
These readings reinforce the lecture and may clarify any concepts from the lecture you might not understand.
- Zhu, N. et al. A Novel Coronavirus from Patients with Pneumonia in China, 2019. Links to an external site. New England Journal of Medicine. Feb 20, 2020.
- Wu, F. et al. A new coronavirus associated with human respiratory disease in China Links to an external site.. Nature. V597. 2020.
- Holshue, M. et al. First Case of 2019 Novel Coronavirus in the United States Links to an external site.. New England Journal of Medicine. Mar 5, 2020.
- WHO: Coronavirus Disease (COVID-19) Pandemic. Links to an external site.2020
- Morens, D. et al. Escaping Pandora’s Box — Another Novel Coronavirus. New England Journal of Medicine. Links to an external site. 2020.
- Kimball, A. et al. Asymptomatic and Presymptomatic SARS-CoV-2 Infections in
Residents of a Long-Term Care Skilled Nursing Facility — King County, Washington, March 2020. CDC MMWR. March 27, 2020. - Anderson, R.M. et al. How will country-based mitigation measures influence the course of the COVID-19 epidemic? Links to an external site. The Lancet Vol 395 March 21, 2020.
- Jin, Y. et al. Virology, Epidemiology, Pathogenesis, and Control of COVID-19 Links to an external site.. Viruses. 12, 372. 2020.
- Roxby, A.C., et al. Detection of SARS-CoV-2 Among Residents and Staff Members of an Independent and Assisted Living Community for Older Adults — Seattle, Washington, 2020. CDC MMWR. April 3, 2020
- Gates, B. Responding to Covid-19 — A Once-in-a-Century Pandemic? New England Journal of Medicine Links to an external site.. Feb 28, 2020.
- Ceraolo, C. and Giorgi, F.M. Genomic variance of the 2019‐nCoV coronavirus Links to an external site.. Journal of Medical Virology. 2020;92:522–528.
- Huang, C. et al. Clinical features of patients infected with 2019 novel
Links to an external site.
coronavirus in Wuhan, China. Links to an external site. The Lancet. Vol 395. February 15, 2020.